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Dihexa was developed from angiotensin IV, a naturally occurring fragment within the renin-angiotensin system

The findings may have implications for the development of innovative approaches in immunology and healthcare, ultimately benefiting patients affected by immune-related disorders and other medical conditions

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(24) investigated plasma mtDNA levels in RA patients and found that RA patients had a high sensitivity to mtDNA copy number compared to healthy controls, and also found that plasma mtDNA concentration was significantly correlated with the Disease Activity Score-28-Erythrocyte Sedimentation Rate (DAS28-ESR), which increased with the increase of DAS28-ESR, thus it is reasonable to believe that plasma mtDNA may be an inflammatory contributor as well as a biomarker in RA